Dean Smith' s team were beaten 2-1 by Brighton in the reverse fixture at Villa Park earlier this season thanks to goals from Danny Welbeck and Solly March.
Villa though have impressed this campaign and are ninth in the table on 35 points from 21 matches and Smith has no new fitness concerns following the home win against Arsenal.
Defender Kortney Hause (foot) is unlikely to return before the end of the month while striker Wesley (knee) is continuing his recovery and is not close to a return following 13 months out.
January signing Morgan Sanson awaits his full debut for the club and Douglas Luiz will be hoping for a recall after being an unused substitute against the Gunners.
Scroll down and click through to see how Villa could line-up for this one
1. Martinez
The former Arsenal goalkeeper was linked with a move to Brighton last summer but opted for Villa and has improved them no end.
2. Matty Cash
Performed well in the Premier League for Villa and another astute signing from the Championship
3. Konsa
Scored against Albion in the reverse fixture and forms a solid defensive barrier alongside Mings
4. Tyrone Mings
The leader in Aston Villa's defence. Strong, powerful and reads the game well